Stem cell derived cell models for drug discovery and cell therapies in Cystic Fibrosis

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PROJECT DESCRIPTION

Cystic Fibrosis is the most common life threatening genetic condition in Australia. There is still no cure. With over ~2000 different CFTR mutations and unknown modifier genes, patient’s clinical response to drugs is heterogeneous. Currently no clinical test exists to predict patient’s response to a modulator drug. We have created a nation-wide biobank of stem cell derived mini-organs from CF patients from 12 CF clinics. They are used in the lab to discover new drugs, to predict an individual CF patients’ response to clinical therapeutic agents or test novel gene therapies.

IDEAL CANDIDATE

The ideal candidate is someone with a proven record of being able to work independently with distant supervision. They have a background in either a medical specialty or bio-informatics with an Hons or Msc in molecular biology. They have experience working as part of a multidisciplinary team. They would have some experience of clinical trials medicine. The ideal candidate has proven verbal and written communication skills and an ability to organise, plan and manage competing tasks. They have procedural skills or an ability to learn and master new techniques/procedures quickly and competently. The ideal candidate would demonstrate a commitment to ongoing professional development. They have experience in submitting research ethics and governance and conducting research according to GCP.
Supervisory team
Shafgah
Waters

Medicine
Women's & Children's Health
Mark
Raftery

Medicine
Medical Sciences
Adam
Jaffe

Medicine
Women's & Children's Health
shafagh.waters@unsw.edu.au