Ocular surface biomarkers for the progression of impaired glucose tolerance

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PROJECT DESCRIPTION

Estimates have indicated that up to 16.4% of Australians have impaired glucose tolerance (IGT) and 11% of this group transition to type 2 diabetes. There have been multiple attempts to identify biomarkers to predict those who are most likely to transition but none are used in routine clinical practice. Identification of those at risk of progressing to type 2 diabetes may allow for targeted strategies to prevent or limit conversion. We hypothesise that the progression from IGT to type 2 diabetes can be predicted by identifying those with early nerve damage using in vivo corneal confocal microscopy and tear analysis.

IDEAL CANDIDATE

The ideal candidate will have a background in optometry or medicine and be registered to use ophthalmic diagnostic drugs in Australia. Excellent verbal and written communication skills are required as the successful candidate will be required to liaise with study participants, endocrinologists, neurologists and optometrists during the course of the research, as well as disseminate the research. Desirable skills include an understanding of biostatistics.
Supervisory team
Maria
Markoulli

Science
Optometry and Vision Science
Arun
Krishnan

Medicine
Prince of Wales Clinical School
Natalie
Kwai

Medicine
Medical Sciences
m.markoulli@unsw.edu.au