Controlling myopia (short-sightedness) by developing a drug-releasing contact lens

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PROJECT DESCRIPTION

Myopia is a major threat for vision health across the world, responsible for approximately 75% of refractive-error-related complications. Myopia is particularly prevalent in Asian societies, with prevalence estimates of over 50% in children in some Asian countries such as China and Singapore. Contact lenses or atropine have been used to prevent the development of myopia. Both reduce myopic progression by 50%. This project will develop potential dual therapy - a contact lens that can deliver atropine to the eye by controlled and sustained release. Materials will be developed that facilitate the uptake and release of atropine. Laboratory studies measuring release kinetics will be followed by applying the drug-releasing lenses onto eyes and monitoring safety and efficacy.

IDEAL CANDIDATE

Candidates from optometric, vision science, pharmacy or materials science backgrounds should consider applying. Experience with hydrogel materials and contact lenses would be an advantage. The ideal candidate will have experience in design of materials for drug release.
Supervisory team
Mark
Willcox

Science
Optometry and Vision Science
Fiona
Stapleton

Science
Optometry and Vision Science
Alex
Hui

Science
Optometry and Vision Science
m.willcox@unsw.edu.au